Oxidative stress and human health taibur rahman ismail hosen m m towhidul islam hossain uddin shekhar ferent human diseases and aging processes many of the recent landmarks in scientific research have shown that in human beings oxidative stress has been implicated in the progression of major health prob lems by inactivating the . Oxidative stress in aging from model systems to human diseases discusses the role of free radicals in aging in different animal models as well as the relevance of free radicals on age related diseases and pathological conditions in humans following an introduction section of the basics and theory of free radicals. The body of literature is now so vast and encompasses so many different techniques and model systems that an integrated evaluation of the evidence is difficult to say the least our goal in writing oxidative stress in aging from model systems to human diseases was to provide an easily accessible assessment of the free radical theory. Oxidative stress aging and cns disease in the canine model of human brain aging the link between aging and oxidative damage suggests the hypothesis that reducing oxidative damage in the brain may lead to improved cognitive function in aged dogs et al proteomic identification of brain proteins in the canine model of human aging . Oxidative stress occurs from the imbalance between rons production and these antioxidant defenses aging is a process characterized by the progressive loss of tissue and organ function the oxidative stress theory of aging is based on the hypothesis that age associated functional losses are due to the accumulation of rons induced damages
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